Phyllanthus emblica herb

The fruit of Phyllanthus umblica is called Indian gooseberry, also known as Amla or amalaki.

Chemical constituents of Phyllanthus emblica.
kaempferol is one of the compounds found in this herb. Phyllanthus umblica has phenols, flavonoids and tannins.

Phyllanthus emblica herb research studies
Modulating effect of Phyllanthus fruit extract against lead genotoxicity in germ cells of mice.
J Environ Biol. 2007. Madhavi D, Devil KR, Rao KK, Reddy PP. Department of Zoology, College of Science, Osmania University, Hyderabad - 500 007, India.
The objective of the present study was to evaluate the protective effect of Phyllanthus emblica against clastogenicity induced by lead nitrate on the incidence of sperm head abnormalities in the germ cells of mice. At higher concentration of lead, a significant increase in the percentage of sperm head abnormalities was noted but when animals primed with Phyllanthus fruit extract, a reduction in the frequency of sperm head abnormalities was observed. It can be suggested from the above study that Phyllanthus emblica plays a key role in inhibition of heavy metal mutagenesis in mammals.

The protective effects of Phyllanthus emblica Linn. extract on ethanol induced rat hepatic injury.
J Ethnopharmacol. 2006. Pramyothin P, Samosorn P, Poungshompoo S, Chaichantipyuth C. Pharmacological Action of Natural Products Research Unit, Department of Pharmacology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.
This study was undertaken to investigate the protective effects of Phyllanthus emblica Linn. extract on ethanol induced rat hepatic injury. Phyllanthus emblica extract (0.5 and 1 mg/ml) increased cell viability of rat primary cultured hepatocytes being treated with ethanol by increasing % MTT and decreasing the release of transaminase. Hepatotoxic markers studied in rats included serum transaminases (AST and ALT), serum triglyceride (STG), hepatic triglyceride (HTG), TNF-alpha and IL-1beta together with histopathological examination. Histopathological studies confirmed the beneficial roles of Phyllanthus emblica extractagainst ethanol induced liver injury in rats.

Spermatotoxic effect of ochratoxin and its amelioration by Emblica officinalis aqueous extract.
Acta Pol Pharm. 2009. Toxicology Division, Department of Zoology, University School of Sciences, Gujarat University, Ahmedabad, India.
The present study was carried out to evaluate the spermatotoxic effect of ochratoxin and it's amelioration by Emblica officinalis aqueous extract. When male albino mice were treated with ochratoxin for 45 days, orally)alterations in various reproductive parameters were observed (sperm count, sperm motility, sperm viability and fertility rate), when further treated with the aqueous extract of Emblica officinalis (2 mg/animal/day for 45 days) amelioration was noted in ochratoxin-induced spermatotoxic effect. Oral administration of ochratoxin for 45 days caused, as compared to vehicle control (Group 2), dose-dependent significant reduction in cauda epididymal sperm count, sperm motility, sperm viability and fertility rate (Groups 4, 5). Oral administration of aqueous extract of Emblica officinalis alone did not cause any significant changes in above mentioned parameters (Group 3). However, Emblica officinalis aqueous extract along with ochratoxin treatment caused significant recovery in all the sperm parameters as well as in fertility rate (Groups 6, 7) in comparison with ochratoxin alone treated animals (Groups 4, 5). Amelioration was higher in high dose ochratoxin plus extract treated animals than that of respective low dose. When normal human sperm cell suspension was treated with ochratoxin (in vitro), various morphological alterations were observed. These were mitigated further, when treated with aqueous extract of Emblica officinalis.

Probiotic prebiotic information